Antioxidant Effect of Three Varieties of Premature Plantain (Musa Paradisiaca) On Oxidative Stress in Alloxan-Induced Diabetic Rats
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Résumé
Effect of antioxidant activities of three different species of premature plantain on oxidative markers in alloxan-induced diabetic rats was studied. Adult albino rats were divided into 5 groups (n=5) and treated as follows: Group 1- Non- diabetic control; Group 2- diabetic control. Both Groups 1 and 2 received standard commercial animal feed only. Group 3 - diabetic rats fed
with premature plantain diet (sample A), Group 4 - diabetic rats fed with premature plantain diet (sample B) and Group 5 - diabetic rats fed with premature plantain diet (sample C). Blood concentration of Malonylaldehyde, glutathione, catalase, sugar, and weight of rats were recorded from each group on the first and last week of the experiment. The proximate analysis and evaluation of in vitro antioxidant activity of the premature plantain samples were undertaken. The diabetic rats placed on premature plantain diet had a decrease in their blood glucose and malonylaldehyde levels with corresponding increase in their weight, glutathione and catalase levels compared with diabetic control rats. The premature plantain extracts also had a high scavenging activity of DPPH radical and high total antioxidant activity. The finding from this study suggested that premature plantain intake may improve the antioxidant status of rats. The three different species of premature plantain used in the study had no significant difference in their nutrients.
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Références
Association of Official Analytical Chemists (1991) Official Method of Analysis W. Horwitz (ed) 13th edn 232-234.
Ayodele, O.H and Godwin V.E (2010) Glycemic indices of processed unripe plantain (Musa paradisiaca) meals. African Journal of Food Sciences 4(8); 514-521
Blanck H,M. (2003) Laboratary issuese: Use of Nutritional Biomakers J. Nutr 13 (3)supp 8885
Biois M.S (1985) Antioxidant determination by use of stable free radicals. Nature 29 1199- 1200
Cerello A., Lizzo S., Bortolo H. and Russa A (1998) Meal generated oxidative stress in type-2 diabetic patients. Diabetes care 21.
-1533
Cohen G, Dembiec D and Marcus J (1970) Measurement of catalase activity in tissue extracts. Analytical Biochemistry 34: 30-38
Craig W. J. (1997)Phytochemicals guardians for our health. J. Am Diet Assoc. 97; 199-204
Dominques C, Ruiz E. Gussinge M (1998) Oxidative stress at on set and early stages of type 1 diabetes in children and adolescents.
Diabetes care 21; 1738-1742
FAO (1990) Roots, Tubers, Ppantains and Banana. Food Nutrition Series 24
Health, R. L and Parker L (1968). Photoperoxidation in isolated chloroplasts. 1 kinetics and stoichiomestry of fatty acid peroxidation. Arch Biochem Biophys 125; 189-198.
Jenkins, D.J.(1981). Glycemic index of foods: A physiological basis for carbohydrate exchange. Am J. of Clin Nutr. 34; 362-366
Kirkosyan A., Seymour E, Kaufman O.B, Warber, S.E and Chang S.C (2003). Antioxidant capacity of polyphynolic extracts from leaves of Cratagus aevigata and Crataegus monogna subject to drought and cold stress. J. Agricultural and food chemistry 51; 3973-3976.
Fleming Niebon B.O, Berg Mikkeloon, Jasper B,N Uelle R.A, and Phillipe C (1997). Malonyladehyde (MDA) as biomarker for oxidative stress. Clin chemistry 43; 7 ,1209-1214
Nourooz Zadeh J.A, Rahim J., Tajaddini Samadi J., Tritshier H., and Roson P (1997). Relationships between plasma measures of
oxidation stress and metabolic control in non –insulin dependent diabetes mellitus Diabetologia. 40; 647-653.
Poliodon M.C, Mecocci P., Stahi W. Parente B and Cecehelti P. (2000). Plasma levels of lipophilic antioxidants in very old patients
with Type 2 diabetes. Diabet Metab. Res. Rev. 316, 15-19
Price K.R, Johnson I.T, and Ferwic C.R (1987). The chemical and biological significance of saponins in food and feeding stuff. Critical Reviews in food science and Nutrition 26: 27, 135-140
Samulsen A.B (2005) Traditional uses, chemical constituents and biological activities of Musa paradisiacal 7; 1-21
Tagami S, Kondo T., Yoshhidfa K and Ohsuka Y.(1992). Effect of insulin on impaired antioxidant activities on aortic endothelial cells from diabetics rabbits Metal 41; 1053-1058
Thomas T.A (1999)Oxidative stress and oxidative defense. In Modern Nutrition in Health and Disease 9th eds. Williams and Williams, Baltimore, M.D 751-760
Udoh A.E, Ntuk I., Essien O and Ndon M. (2007). Red cell catalase activity in diabetics . J. Nutrition 6 (5); 511-515
World Health Organisation (2003). Diagnosis and classification of diabetes mellitus. Geneva World Health Organisation.