Antioxidant Effect of Three Varieties of Premature Plantain (Musa Paradisiaca) On Oxidative Stress in Alloxan-Induced Diabetic Rats

Main Article Content

A. J. Ekpo
E. O. Jimmy

Abstract

Effect of antioxidant activities of three different species of premature plantain on oxidative markers in alloxan-induced diabetic rats was studied. Adult albino rats were divided into 5 groups (n=5) and treated as follows: Group 1- Non- diabetic control; Group 2- diabetic control. Both Groups 1 and 2 received standard commercial animal feed only. Group 3 - diabetic rats fed
with premature plantain diet (sample A), Group 4 - diabetic rats fed with premature plantain diet (sample B) and Group 5 - diabetic rats fed with premature plantain diet (sample C). Blood concentration of Malonylaldehyde, glutathione, catalase, sugar, and weight of rats were recorded from each group on the first and last week of the experiment. The proximate analysis and evaluation of in vitro antioxidant activity of the premature plantain samples were undertaken. The diabetic rats placed on premature plantain diet had a decrease in their blood glucose and malonylaldehyde levels with corresponding increase in their weight, glutathione and catalase levels compared with diabetic control rats. The premature plantain extracts also had a high scavenging activity of DPPH radical and high total antioxidant activity. The finding from this study suggested that premature plantain intake may improve the antioxidant status of rats. The three different species of premature plantain used in the study had no significant difference in their nutrients.

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Ekpo, A. J., & Jimmy, E. O. (2014). Antioxidant Effect of Three Varieties of Premature Plantain (Musa Paradisiaca) On Oxidative Stress in Alloxan-Induced Diabetic Rats. Nigerian Journal of Pharmaceutical and Applied Science Research, 3(2), 8–16. Retrieved from http://mail.nijophasr.net/index.php/nijophasr/article/view/61
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Articles
Author Biographies

A. J. Ekpo

Department of Biochemistry, Faculty of Basic Medical Science, University Of Uyo, Akwa Ibom State, Nigeria.

E. O. Jimmy

Department Of Physiology, Faculty of Basic Medical Science, University Of Uyo, Akwa Ibom State, Nigeria

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