Antibacterial Potential of Ginger (Zingiber officinale) Extract against Bacterial Isolates of Pulmonary Infections

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Johnson D. Jemikalajah
Felix O. Enwa
Clement O. Anie
G. Ray Okogun

Résumé

There has been a lot of interest in the investigation of natural materials as sources of new antibacterial agents. Therefore, this study aims at the determination of antibacterial potential of ginger extracts against bacteria isolates of pulmonary infections. The ginger rhizome, used in the study was obtained at the botanical garden of the Department of Pharmacognosy Delta State University Abraka where extraction processes were also carried out using methanol, and sterile distilled water. Standard bacteriological culture method was used for isolation of bacteria from the pulmonary infections. Three isolates of Streptococcus pneumonia (5.66%), six strains of Klebsiella pneumonia (11.32%), sixteen strains of Staphylococcus aureus (30.18%), ten isolates of Escherichia coli (18.86%), ten strains of Pseudomonas aeruginosa (18.86%) and eight isolates of Proteus mirabilis (15.09%) were tested against extracts of ginger using agar diffusion plate method. The result revealed a significant effect of methanol extracts of the ginger in all the isolates tested, but there were some resistant strains observed in the conventional antibiotics; while the sensitivity pattern of crude extract of ginger were less effective compared to methanol extract. The present work indicates that natural rhizome (ginger) has considerable antibacterial activities against bacterial isolates of pulmonary infections.

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Jemikalajah, J. D. ., Enwa, F. O., Anie, C. O. ., & Okogun, G. R. (2020). Antibacterial Potential of Ginger (Zingiber officinale) Extract against Bacterial Isolates of Pulmonary Infections. Nigerian Journal of Pharmaceutical and Applied Science Research, 8(2), 62–66. Consulté à l’adresse http://mail.nijophasr.net/index.php/nijophasr/article/view/293
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Bibliographies de l'auteur-e

Johnson D. Jemikalajah

Department of Microbiology, Delta State University, Abraka

Felix O. Enwa

Department of Pharmaceutical Microbiology, Delta State University, Abraka.

Clement O. Anie

Department of Pharmaceutical Microbiology, Delta State University, Abraka.

G. Ray Okogun

Department of Medical Laboratory Science, Ambrose Alli University, Ekpoma

Références

Argento, A., Tiraferri, E., Marzaloni, M.(2000): Oral anticoagulant and medicinal plants, an emerging interaction.Ann. Ital. Med. Int; 15(20):139-143.

Baker, F.J., Breach, M.P. and Leighton, P.T. (1980):MedicalMicrobiologyTechniques,London Boston SydneyWellington Durham-Toronto, 4th Edition, Pp.,425.

Chinese researchers(2001): Medicinal plant of the world. Special herbal Supplies, 2.

Cowan, S.T. and Steel, K.J. (1974): Identification of medical bacterial, 2nd edition, Cambridge University Press, (London) pp46-81.

Cruikshank, R.,Duguid, J.P., Mamion, B.P. (1975): Medical microbiology. Vol.2, 12th edition, Churchill Livingstone.Pp428-434.

Cheesbrough, M. (2000): District laboratory practice in tropical countries, United Kingdom Cambridge University Press, pg 157-164.

Cooper, R.J., Hoffman,J.R., Bartlett,J.G., Besser,R.E., Conzalez,R. Hickner, J.M. (2001): Principles of appropriate antibiotic use for acute pharyngitis in adults: background. Ann. Intern. Med; 134:509-517.

Furman, B., Rosenblat, M., Hayek, T. (2000): Ginger extract consumption reduces plasma cholesterol, inhibits L:DL oxidation and attenuates development of atherosclerotic apolipoprotein in deficient mice. J. Nutr.130(5): 1124-1131.

Govindarajan, V. (1992): Ginger-Chemistry, technology and quality evaluation: Part 1 CRC Critical Review in Food Science and Nutrition. 19:1-96.

Langer, E., Greifenberg,S. Grnenwald, J. (1998): Ginger: history and use. Adv. Ther. 15(1): 25-44.

Shoji, N. andIwassa, A. (1982): Cardiotonic principle of ginger. J. Phar. Sci. 71(10):1174-1175.

Slack, R.C.B. and Greenwood, D. (2002): Infective syndrome: Medical Microbiology: A guide to microbial infections; pathogenesis immunity. Laboratory Diagnosis and control. Edinburgh, Churchill Livingstone.

UmaPradeep, K., Geervni, P., Egguon, B.V. (1993): Common Indian Species: Nutrient Composition, Consumption and Contribution to dietary value. Pant Foods Hum Nutr;44(2): 137-148.

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